The 1963 Clemson-South Carolina Game

24 - 20 Clemson

On November 23, 1963, the Tigers and Gamecocks were set to play the annual rivalry on live national TV. However, the assassination of President John F. Kennedy the day before would affect the scheduling of the game. Both schools planned to proceed with the original day and time, but federal government pressure caused the schools to push the game to November 28, marking the only time Clemson and Carolina played on Thanksgiving Day. Clemson won the game 24–20.

Source: Wikipedia