The 1980 Clemson-South Carolina Game
27 - 6 Clemson
In the last regular season game for the 1980 season, a heavily favored Carolina team traveled to Death Valley to take on the Tigers. In a surprise to both the players and the fans, Coach Danny Ford unveiled new orange uniform pants for the Tigers to wear. This was the first time in Clemson’s history that they wore orange pants in any combination for a football game. Inspired by the pants, the underdog Tigers defeated the Gamecocks, 27–6.
Source: Wikipedia